UNG1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityUNG1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionUNG1 Antibody: The human uracil-DNA glycosylase (UNG) gene encodes both mitochondrial (UNG1) and nuclear (UNG2) forms through differentially regulated promotes and alternative splicing. While UNG2 is the major enzyme in the base excision repair pathway that removes uracil residues from nuclear DNA that arise through either misincorporation during replication or cytosine deamination, inhibition of UNG1 by uracil glycosylase inhibitor did not lead to increased levels of spontaneous or induced mitochondrial DNA mutations. However, decreased levels of UNG activity and increased oxidative damage to mitochondrial DNA were seen in older mice, suggesting that mitochondrial DNA repair mechanisms may be involved in various neurodegenerative disorders
ImmunogenImmunogen: UNG1 antibody was raised against a 13 amino acid synthetic peptide from near the amino terminus of human UNG1. Buffer: UNG1 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[UNG1; DGU; UDG; UNG1; UNG2; HIGM4; HIGM5; UNG15; DGU; Uracil-DNA glycosylase; uracil-DNA glycosylase], [UNG; UNG; DGU; UDG; UNG1; UNG2; HIGM4; HIGM5; UNG15;]
Gene, Accession #[UNG], Gene ID: 7374, NCBI: NP_003353, UniProt: P13051
Catalog #MBS150242
Price$375
Order / More InfoUNG1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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