Phospho-APP-T743 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-APP-T743
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse, rat
Isotypen/a
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB)
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DescriptionThis gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.
ImmunogenImmunogen: A phospho specific peptide corresponding to residues surrounding T743 of human APP Calculated Molecular Weight: 87kDa
Other Names[Phospho-APP-T743: AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma], [APP; APP; AAA; AD1; PN2; ABPP; APPI; CVAP; ABETA; PN-II; CTFgamma; A4; AD1; APP; CVAP; PN-II; S-APP-alpha; S-APP-beta; AICD-59; AID(59); AICD-57; AID(57); AICD-50; AID(50)]
Gene, Accession #[APP], Gene ID: 351, NCBI: P05067.3, UniProt: P05067
Catalog #MBS125591
Price$235, $350, $525
Order / More InfoPhospho-APP-T743 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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