GluR4/AMPA4 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | GluR4/AMPA4 |
| Clone | polyclonal |
| Host Species | Goat |
| Reactive Species | human, mouse, rat, bovine |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Human glutamate receptor 4 (GRIA4) is a new member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. Binding studies showed that human GluR4 transfected into simian kidney cells (COS-1) exhibits high specific binding for[3H](RS)-alpha-amino- 3-hydroxy-5-methylisoxazole-4-propionic acid ([3H]AMPA) but not [3H]kainate. Ion substitution experiments indicate that hGluR4 receptor-linked ion channels in their homomeric state are permeable to both CA2+ and Na+ ions. Immunoprecipitation studies suggest that GRIA1 exists in situ in the form of a pentamer. Nociceptors, involved primarily in the mediation of neuropathic pain, may be presynaptically modulated by GluR4 |
| Immunogen | Immunogen: Synthetic peptide: C-KKLDQREYPGSETP, from the internal region of the protein sequence according to NP_000820.3; NP_001070711.1; NP_001070712.1. |
| Other Names | [glutamate receptor 4 isoform 1; Glutamate receptor 4; glutamate receptor 4; glutamate ionotropic receptor AMPA type subunit 4; AMPA-selective glutamate receptor 4; GluR-D; Glutamate receptor ionotropic, AMPA 4], [GRIA4; GRIA4; GLUR4; GLURD; GluA4; GLUR4C; NEDSGA; GLUR4; GluR-4; GluR4; GluA4] |
| Gene, Accession # | [GluR4/AMPA4], Gene ID: 2893, NCBI: NP_000820.3, UniProt: P48058 |
| Catalog # | MBS555915 |
| Price | $425 |
| Order / More Info | GluR4/AMPA4 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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