Mouse P2X7 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Mouse P2X7 |
| Clone | [Hano43] |
| Host Species | Rat |
| Reactive Species | n/a |
| Isotype | IgG2b |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | IgG concentration 1.0mg/ml |
| Applications | Flow cytometry (FC/FACS), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rat anti Mouse P2X7 antibody, clone Hano43 recognizes the P2X purinoceptor 7, also known as P2X7. The P2X7 ATP receptor has a distinctive long C-terminal tail with multiple potential protein and lipid interaction motifs and is highly polymorphic. It is a cation selective ion channel that opens up on binding of extracellular ATP. Sustained activation by extracellular ATP results in the formation of a reversible pore in the plasma membrane that is permeable to hydrophilic solutes of up to 900 Da. Once a pore is opened massive upset of cytoplasmic ion homeostasis occurs and the pore stays open as long as it is bound by ATP. Should ATP stimulation continue the cell will become irreversibly damaged and die. P2X7 plays a key role in the maturatio |
| Immunogen | Immunogen: A P2X7-expression construct and a final boost with P2X7-transfected HEK cells. Fusion Partners: Spleen cells from immunised rats were fused with cells of the Sp2/0 myeloma cell line. Buffer Solution: Phosphate buffered saline Target Species: Mouse |
| Other Names | [P2X purinoceptor 7 isoform a; P2X purinoceptor 7; P2X purinoceptor 7; ATP receptor; P2X7 purinoceptor; P2X7 receptor; P2Z receptor; purinergic receptor P2X, ligand-gated ion channel, 7; ATP receptor; P2Z receptor; Purinergic receptor], [P2rx7; P2rx7; P2X7R; P2X(7); AI467586; P2x7; P2X7] |
| Gene, Accession # | [P2X7], Gene ID: 18439, NCBI: NP_035157.2, UniProt: Q9Z1M0 |
| Catalog # | MBS219463 |
| Price | $300 |
| Order / More Info | Mouse P2X7 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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