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Antigenic Specificity | RAD51 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b,k |
Format | unconjugated |
Size | 0.05 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This RAD51 antibody is generated from a mouse immunized with a recombinant protein between 1-339 amino acids from human RAD51. Participates in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex DNA and forms helical nucleoprotein filaments. Part of a PALB2- scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3. |
Immunogen | n/a |
Other Names | [DNA repair protein RAD51 homolog 1; HsRAD51; hRAD51; RAD51 homolog A; RAD51; RAD51A; RECA] |
Gene, Accession # | [RAD51], Gene ID: 5888, NCBI: NP_001157741.1, UniProt: Q06609 |
Catalog # | MBS9217070 |
Price | $165, $370 |
Order / More Info | RAD51 Antibody from MYBIOSOURCE INC. |
Product Specific References | Shinohara A.,et al.Nat. Genet. 4:239-243 (1993). Yoshimura Y.,et al.Nucleic Acids Res. 21:1665-1665 (1993). Schmutte C.,et al.Cancer Res. 59:4564-4569 (1999). Wang W.W.,et al.Cancer Epidemiol. Biomarkers Prev. 10:955-960 (2001). Park J.Y.,et al.Nucleic Acids Res. 36:3226-3234 (2008). |