rat Sortilin Antibody from MYBIOSOURCE INC.

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Antigenic Specificityrat Sortilin
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesrat
Isotypen/a
Formatperoxidase (HRP) conjugate
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA)
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DescriptionFunctions as a sorting receptor in the Golgi compartment and as a clearance receptor on the cell surface. Required for protein transport from the Golgi apparatus to the lysosomes by a pathway that is independent of the mannose-6-phosphate receptor (M6PR). Also required for protein transport from the Golgi apparatus to the endosomes. Promotes neuronal apoptosis by mediating endocytosis of the proapoptotic precursor forms of BDNF (proBDNF) and NGFB (proNGFB). Also acts as a receptor for neurotensin. May promote mineralization of the extracellular matrix during osteogenic differentiation by scavenging extracellular LPL. Probably required in adipocytes for the formation of specialized storage vesicles containing the glucose transporter SLC2A4/G
ImmunogenImmunogen: Recombinant rat Sortilin protein(610-754aa)
Other Names[Glycoprotein 110; Neurotensin receptor 3; Sort1], [Sort1; Sort1; Nt3; Nts3; Gp110; NTR3]
Gene, Accession #Gene ID: 83576, NCBI: NP_113955.1, UniProt: O54861
Catalog #MBS1492585
Price$160, $235
Order / More Inforat Sortilin Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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