CD25 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityCD25
ClonePC61
Host SpeciesRat
Reactive Speciesmouse
IsotypeIgG1 lambda
Formatallophycocyanin (APC) conjugate
Size100 µg
Concentration0.2 mg/mL
ApplicationsFlow Cytometry
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DescriptionAllophycocyanin conjugated CD25 Monoclonal Antibody was Protein G Purified from tissue culture supernatant and is directed against mouse CD25. Reactivity is observed against mouse CD25. Cross reactivity with CD25 from other sources has not been tested. CD25 is a 55KDa transmembrane glycoprotein consisting of a heavily glycosylated extracellular domain, a transmembrane region and a short cytoplasmic tail. It is expressed during early stages of thymocytes development and in activated CD4+ memory T-lymphocytes. CD25 heterodimerizes with IL2R-beta and IL-2R gamma and forms the tripartite high affinity IL-2 receptor complex. It increases the specificity and affinity of IL-2 receptor complex for IL-2 ligand and is necessary for receptor clustering required for augmentation of IL-2 signaling. Mutations in CD25 result in severe immunodeficiency.
ImmunogenAnti-CD25 Antibody (Monoclonal) was produced by repeated immunizations with IL-2-dependent cytolytic mouse T-cell clone B6.1.
Other NamesInterleukin-2 receptor subunit alpha, IL-2 receptor subunit alpha, IL-2-RA, IL-2R subunit alpha, IL2-RA, TAC antigen, p55, CD25 Antibody
Gene, Accession #Il2r, Gene ID: 16184, NCBI: NP_032393.3, UniProt: P01590
Catalog #200-526-M73
Price$495
Order / More InfoCD25 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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