CD80 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
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| Antigenic Specificity | CD80 |
| Clone | 16-10A1 |
| Host Species | Hamster Armenian |
| Reactive Species | mouse |
| Isotype | IgG |
| Format | fluorescein (FITC) conjugate |
| Size | 500 µg |
| Concentration | 0.5mg/mL |
| Applications | Flow Cytometry, Immunohistochemistry, IF Microscopy, Immunoprecipitation |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Fluorescein conjugated CD80 Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against mouse CD80. Cross reactivity with CD80 from other sources has not been tested. Anti-CD80 is conjugated with FITC under optimal conditions and the solution is free of unconjugated FITC. Anti-CD80 antibody reacts with mouse CD80, also known as B7-1, a 55 kDa type I transmembrane protein ligand for CD152 (CTLA-4) and for CD28, a co-stimulatory receptor for the T cell receptor (TCR). CD28 also binds a second B7 ligand known as CD86 (B7-2). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 or CTLA-4 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response. |
| Immunogen | Anti-CD80 Antibody (Monoclonal) was produced by repeated immunizations with CD80 antigen. |
| Other Names | T-lymphocyte activation antigen CD80, Activation B7-1 antigen, B7, CD80, Cd80 |
| Gene, Accession # | Cd80, Gene ID: 12519, NCBI: NP_033985.3, UniProt: Q00609 |
| Catalog # | 200-B02-N89 |
| Price | $365 |
| Order / More Info | CD80 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
| Product Specific References | n/a |
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654
orders@rockland.com
Technical Support: tech@rockland.com
https://www.rockland.com/
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