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Antigenic Specificity | CD62L |
Clone | DREG-56 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 kappa |
Format | allophycocyanin (APC) conjugate |
Size | 500 µL |
Concentration | n/a |
Applications | Flow Cytometry, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Allophycocyanin conjugated CD62L Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against human CD62L. Reactivity is observed against human CD62L. Cross reactivity is observed with Chimpanzee and bovine. Reactivity with CD62L from other sources has not been tested. Anti-CD62L is conjugated with APC under optimal conditions and the solution is free of unconjugated APC. CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naive lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells. |
Immunogen | Anti-CD62L Antibody (Monoclonal) was produced by repeated immunizations with CD62L antigen. |
Other Names | L-selectin, CD62 antigen-like family member L, Leukocyte adhesion molecule 1, LAM-1, Leukocyte surface antigen Leu-8, Leukocyte-endothelial cell adhesion molecule 1, LECAM1, Lymph node homing receptor, TQ1, gp90-MEL, CD62L , SELL , LNHR, LYAM1 |
Gene, Accession # | SELL, Gene ID: 6402, NCBI: NP_000646.2, UniProt: P14151 |
Catalog # | 200-326-N72 |
Price | $585 |
Order / More Info | CD62L Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |