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Antigenic Specificity | CD80 |
Clone | 16-10A1 |
Host Species | Hamster Armenian |
Reactive Species | mouse |
Isotype | IgG |
Format | allophycocyanin (APC) conjugate |
Size | 100 µg |
Concentration | 0.2mg/mL |
Applications | Flow Cytometry, Immunohistochemistry, Immunoprecipitation |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Allophycocyanin conjugated CD80 Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against mouse CD80. CD80 has cross reactivity with canine; cross reactivity from other sources has not been tested. Anti-CD80 is conjugated with APC under optimal conditions and the solution is free of unconjugated APC. CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells. |
Immunogen | Anti-CD80 Antibody (Monoclonal) was produced by repeated immunizations with CHO cell line transfected with mouse B7 (CD80). |
Other Names | T-lymphocyte activation antigen CD80, Activation B7-1 antigen, B7, CD80, Cd80 |
Gene, Accession # | Cd80, Gene ID: 12519, NCBI: NP_033985.3, UniProt: Q00609 |
Catalog # | 200-B26-N89 |
Price | $545 |
Order / More Info | CD80 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |