CD80 Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityCD80
Clone16-10A1
Host SpeciesHamster Armenian
Reactive Speciesmouse
IsotypeIgG
Formatallophycocyanin (APC) conjugate
Size100 µg
Concentration0.2mg/mL
ApplicationsFlow Cytometry, Immunohistochemistry, Immunoprecipitation
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DescriptionAllophycocyanin conjugated CD80 Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against mouse CD80. CD80 has cross reactivity with canine; cross reactivity from other sources has not been tested. Anti-CD80 is conjugated with APC under optimal conditions and the solution is free of unconjugated APC. CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
ImmunogenAnti-CD80 Antibody (Monoclonal) was produced by repeated immunizations with CHO cell line transfected with mouse B7 (CD80).
Other NamesT-lymphocyte activation antigen CD80, Activation B7-1 antigen, B7, CD80, Cd80
Gene, Accession #Cd80, Gene ID: 12519, NCBI: NP_033985.3, UniProt: Q00609
Catalog #200-B26-N89
Price$545
Order / More InfoCD80 Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
ROCKLAND IMMUNOCHEMICALS INC.
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

orders@rockland.com
Technical Support: tech@rockland.com

https://www.rockland.com/

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