Microtubule Associated Protein 2 (MAP2) Antibody from ROCKLAND IMMUNOCHEMICALS INC.

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Antigenic SpecificityMicrotubule Associated Protein 2 (MAP2)
Host SpeciesChicken
Reactive Speciesbovine, human, mouse, rat
FormatIgY fraction
Size100 µl
ConcentrationTitrated value sufficient to run approximately 10 mini blots.
ApplicationsIF Microscopy,Western Blot,
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DescriptionAnti-Microtubule Associated Protein 2 (MAP2) (Chicken) Antibody - 200-901-D68. Anti-MAP2 antibody is directed agaist MAP2 protein. The antibody is a total IgY fraction. The antibody has been directly tested for reactivity in bovine, human, mouse and rat tissues. It is expected that the antibody will react with other mammalian tissues. Cross reactivity with MAP2 from other species has not been determined. MAP2 antibody detects Microtubule Associated Protein 2. Microtubules are 25nm diameter protein rods found in most kinds of eukaryotic cells. They are polymerized from a dimeric subunit made of one a subunit and one b tubulin subunit. Microtubules are associated with a family of proteins called microtubule associated proteins (MAPs), which includes the protein τ (tau) and a group of proteins referred to as MAP1, MAP2, MAP3, MAP4 and MAP5. MAP2 is made up of two ~280kDa apparent molecular weight bands referred to as MAP2a and MAP2b. A third lower molecular weight form, usually called MAP2c, corresponds to a pair of protein bands running at ~70kDa on SDS-PAGE gels. All these MAP2 forms are derived from a single gene by alternate transcription, and all share a C-terminal sequence which includes either three or four microtubule binding peptide sequences, which are very similar to those found in the related microtubule binding protein τ (tau). MAP2 isoforms are expressed only in neuronal cells and specifically in the perikarya and dendrites of these cells. MAP2 has been recently shown to be the specific receptor for the neurosteroid pregnenolone.
ImmunogenAnti-Microtubule Associated Protein 2 Antibody was produced in chicken by repeated immunizations with recombinant bovine MAP2 protein expressed in and purified from E. Coli.
Other NamesMicrotubule-associated protein 2, MAP2, MAP-2,Map2, Map-2
Gene, Accession #MAP2, Gene ID: 4133, UniProt: P11137, NCBI: DAA32510.1
Catalog #200-901-D68
Order / More InfoMicrotubule Associated Protein 2 (MAP2) Antibody from ROCKLAND IMMUNOCHEMICALS INC.
Product Specific Referencesn/a
PO Box 5199
Limerick PA 19468
P: 484-791-3823
P: 800.656.7625
F: 484.369.8654

Technical Support: tech@rockland-inc.com


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