Edit |   |
---|---|
Antigenic Specificity | HP1 alpha, beta, gamma |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 50 µg |
Concentration | 2.0 µg/µL |
Applications | Chip, IF Microscopy, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-HP1 alpha, beta, gamma Antibody was purified by Protein G chromatography. Cross-reactivity with HP1 α, β, G from species other than human has not been determined. HP1 alpha, beta and gamma (UniProt/Swiss-Prot entry P45973, P83916 and Q13185) are components of heterochromatin. They recognize and bind histone H3 tails methylated at `Lys-9', leading to epigenetic repression of transcription. HP1 alpha, beta and gamma also interact with lamin B receptor (LBR), thereby contributing to the association of heterochromatin with the innernuclear membrane. Anti-HP1 α, β, g Antibody is ideal for research in Chromatin Remodeling and Epigenetics. |
Immunogen | Anti-HP1 α, β, g Antibody was produced in rabbits by repeated immunization with a full length recombinant protein of human HP1 beta. The antibody also recognizes the alpha and gamma isoforms. |
Other Names | Chromobox protein homolog 1, HP1Hsbeta, Heterochromatin protein 1 homolog beta, HP1-beta, Heterochromatin protein p25, M31, Modifier 1 protein, p25 beta |
Gene, Accession # | CBX1, Gene ID: 10951, NCBI: NP_001120700, UniProt: P83916 |
Catalog # | 200-401-V35 |
Price | $455 |
Order / More Info | HP1 alpha, beta, gamma Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |