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Antigenic Specificity | CD62L |
Clone | MEL-14 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a kappa |
Format | allophycocyanin (APC) conjugate |
Size | 100 µg |
Concentration | 0.2 mg/mL |
Applications | Flow Cytometry, Immunohistochemistry, Immunoprecipitation |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Allophycocyanin conjugated CD62L Monoclonal Antibody was purified from tissue culture supernatant via affinity chromatography and is directed against mouse CD62L. Cross reactivity with CD62L from other sources has not been tested. Anti-CD62L is conjugated with APC under optimal conditions and the solution is free of unconjugated APC. Anti-CD62L antibody is specific for mouse CD62L, also known as L-Selectin, a cell adhesion molecule which facilitates lymphocyte rolling on activated vascular endothelium and homing to high endothelial venules (HEV) as immune cells transmigrate from blood into peripheral tissues. L-Selectin is a member of a family of Selectin molecules which act together with the integrin family of adhesion molecules to mediate leukocyte-endothelial interactions. L-Selectin is characteristically expressed by neutrophils, and is also found on B cells, monocytes, granulocytes, and at varying levels on naive, effector and memory T cells. It is rapidly shed upon cell activation, releasing into the circulation a soluble form whose biological role is of particular interest in cancer biology research. The MEL-14 antibody may be used as a phenotypic marker for CD62L expression on a variety of immune cell types. Please note that CD62L (L-Selectin) itself is also referred to as MEL-14 in the literature. |
Immunogen | Anti-CD62L Antibody (Monoclonal) was produced by repeated immunizations with CD62L antigen. |
Other Names | L-selectinCD62 antigen-like family member LLeukocyte adhesion molecule 1LAM-1Leukocyte-endothelial cell adhesion molecule 1LECAM1Lymph node homing receptorLymphocyte antigen 22Ly-22Lymphocyte surface MEL-14 antigenCD62L Sell Lnhr, Ly-22, Ly22 |
Gene, Accession # | Sell, Gene ID: 20343, NCBI: NP_035476.1, UniProt: P18337 |
Catalog # | 200-526-N87 |
Price | $369 |
Order / More Info | CD62L Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |