MAP2 Antibody from ST JOHN'S LABORATORY

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Antigenic SpecificityMAP2
Clonepolyclonal
Host SpeciesChicken
Reactive Speciesn/a
Isotypen/a
FormatIgY fraction
Size100µl
Concentrationn/a
Applicationsvalidated: WB, IF. RUO
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DescriptionMicrotubules are 25nm diameter protein rods found in most kinds of eukaryotic cells. They are polymerized from a dimeric subunit made of one a subunit and one b tubulin subunit. Microtubules are associated with a family of proteins called microtubule associated proteins (MAPs), which includes the protein tau (tau) and a group of proteins referred to as MAP1, MAP2, MAP3, MAP4 and MAP5 (Kindler & Gardner 1994). MAP2 was made up of two ~280 kDa apparent molecular weight bands referred to as MAP2a and MAP2b. A third lower molecular weight form, usually called MAP2c, corresponds to a pair of protein bands running at ~70 kDa on SDS-PAGE gels. All these MAP2 forms are derived from a single gene by alternate transcription, and all share a C-terminal sequence which includes either three or four microtubule binding peptide sequences, which are very similar to those found in the related microtubule binding protein tau (tau). MAP2 isoforms are expressed only in neuronal cells and specifically in the perikarya and dendrites of these cells. MAP2 has been recently shown to be the specific receptor for the neurosteroid pregnenolone (Fontaine-Lenore V. et al., 2006).
Immunogenrecombinant bovine MAP2 protein expressed in and purification from E. coli.
Other NamesMicrotubule-associated protein 2 , MAP-2
Gene, Accession #MAP2, Gene ID: 4133, SwissProt: P11137_HUMAN
Catalog #STJ120119
Price£270
Order / More InfoMAP2 Antibody from ST JOHN'S LABORATORY
Product Specific Referencesn/a
ST JOHN'S LABORATORY
ST JOHN'S LABORATORY
ST JOHN'S LABORATORY
Knowledge Dock Business Centre
Docklands Campus, University Way
London, E16 2RD UK
P: +44 (0)208 223 3081
F: +44 (0)207 681 2580

info@stjohnslabs.com
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https://www.stjohnslabs.com

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