Phosphotyrosine Antibody from STRESSMARQ BIOSCIENCES INC.

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Antigenic SpecificityPhosphotyrosine
CloneG104
Host SpeciesMouse
Reactive Speciesn/a
IsotypeIgG1
FormatATTO 488 conjugate
Size100 µg
Concentration1 mg/ml
ApplicationsWB, IHC, ICC/IF, IP
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DescriptionMouse Anti- Phosphotyrosine Monoclonal IgG1. Reacts with phosphotyrosine, and detects the presence of phosphotyrosine in both un-stimulated and stimulated cell lysates. Does not cross-react with phosphoserine or phosphothreonine. Protein phosphorylation is an important posttranslational modification that serves many key functions to regulate a protein?s activity, localization, and protein-protein interactions. Phosphorylation is catalyzed by various specific protein kinases, which involves removing a phosphate group from ATP and covalently attaching it to to a recipient protein that acts as a substrate. Most kinases act on both serine and threonine; others act on tyrosine, and a number (dual
ImmunogenPhosphotyrosine, alanine and glyceine in a 1:1:1 ratio polymerized in the presence of keyhole limpet hemocyanin with 1-ethyl-3-(3?-dimentrylaminopropyl) carbodiimide
Other NamesPhosphoTyrosine (pY), PhosphoTyrosine (pY)
Gene, Accession #n/a
Catalog #SMC-174D-A488
Price$337 US
Order / More InfoPhosphotyrosine Antibody from STRESSMARQ BIOSCIENCES INC.
Product Specific References1. Garton A.J., Flint A.J., and Tonks N.K. (1996) Mol and Cell Bio 16(11): 6408-6418. 2. Garton A.J., and Tonks N.K. (1999) J Bio Chem. 274(6): 3811-3818. 3. Goto H. et al. (2005) Nature Cell Biology 8: 180-187. 4. Blume-Jensen P. and Hunter T. (2001) Nature 411: 355-365. 5. Downward J. (2001) Nature 411: 759-762. 6. Pawson T. and Saxton T.M. (1999) Cell 97: 675-678. 7. Frackelton A.R. Jr., Ross A.H., and Eisen H.N. (1983) Mol Cell Biol. 3: 1343-1352. 8. Ross A.H., Baltimore D., and Eisen H.N. (1981) Nature 294: 654-656. 9. Tiganis T., Kemp B.E., and Tonks N.K. (1999) J. Bio Chem. 274(39): 27768-27775.
STRESSMARQ BIOSCIENCES INC.
STRESSMARQ BIOSCIENCES INC.
STRESSMARQ BIOSCIENCES INC.
PO Box 55036
Cadboro Bay
Victoria BC V8N4G0 CANADA
P: +1-250-294-9065
F: +1-250-294-9025

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