SARS-CoV-2 Spike Trimer Protein (T19R, T95I, Y145H, EF156-157del, R158G, A222V, L452R, T478K, D614G, P681R, D950N), His Tag (MALS verified) from ACROBIOSYSTEMS USA
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| Product Name | SARS-CoV-2 Spike Trimer Protein (T19R, T95I, Y145H, EF156-157del, R158G, A222V, L452R, T478K, D614G, P681R, D950N), His Tag (MALS verified) |
| Description | SARS-CoV-2 Spike Trimer, His Tag (SPN-C52Hu) is the ectodomain of SARS-CoV-2 S protein which contains AA Val 16 - Pro 1213 (Accession # QHD43416.1). The mutations T19R, T95I, Y145H, EF156-157del, R158G, A222V, L452R, T478K, D614G, P681R, D950N were identified in the SARS-CoV-2 Delta Plus variant (Pango lineage: AY.4.2). The recombinant protein is expressed from human 293 cells (HEK293) with T4 fibritin trimerization motif and a polyhistidine tag at the C-terminus. Proline substitutions (F817P, A892P, A899P, A942P, K986P, V987P) and alanine substitutions (R683A and R685A) are introduced to stabilize the trimeric prefusion state of SARS-CoV-2 S protein and abolish the furin cleavage site, respectively. This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 137.8 kDa. The protein migrates as 160-200 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. Purity: 95% |
| Size | 500ug |
| Concentration | n/a |
| Applications | n/a |
| Other Names | recombinant protein |
| Gene, Accession, CAS # | Accession: QHD43416.1 |
| Catalog # | SPN-C52Hu-500ug |
| Price | $3080 |
| Order / More Info | SARS-CoV-2 Spike Trimer Protein (T19R, T95I, Y145H, EF156-157del, R158G, A222V, L452R, T478K, D614G, P681R, D950N), His Tag (MALS verified) from ACROBIOSYSTEMS USA |
| Product Specific References | n/a |
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