IRL 2500 from ALOMONE LABS

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Product NameIRL 2500
DescriptionIRL 2500 is a potent antagonist of endothelin ET-B receptors, exhibiting selectivity for ET-B over ET-A receptors when inhibiting the binding of [125I]-Endothein-1 (IC50 of 1.3 nM and 94 nM, respectively). IRL 2500 attenuates the effects of ETB-selective agonists in vitro and in-vivo, such as saraphotoxin S6c-mediated dog saphenous vein contraction or IRL-1620-induced transient decrease in arterial pressure and increase in renal vascular resistance in rat1,2. Synthetic. Purity >97%. MW: 573.69
Size10 mg
Concentration0.1-10 µM.
Applicationsn/a
Other Namesn/a
Gene, Accession, CAS #CAS: 169545-27-1
Catalog #I-190
Priceplease inquire
Order / More InfoIRL 2500 from ALOMONE LABS
Product Specific Referencesn/a
ALOMONE LABS
ALOMONE LABS
ALOMONE LABS
Jerusalem BioPark (JBP), Hadassah Ein Kerem
PO Box 4287
Jerusalem, 9104201 ISRAEL
P: +972-2-587-2202
F: +972-2-587-1101

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