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Product Name | IRL 2500 |
Description | IRL 2500 is a potent antagonist of endothelin ET-B receptors, exhibiting selectivity for ET-B over ET-A receptors when inhibiting the binding of [125I]-Endothein-1 (IC50 of 1.3 nM and 94 nM, respectively). IRL 2500 attenuates the effects of ETB-selective agonists in vitro and in-vivo, such as saraphotoxin S6c-mediated dog saphenous vein contraction or IRL-1620-induced transient decrease in arterial pressure and increase in renal vascular resistance in rat1,2. Synthetic. Purity >97%. MW: 573.69 |
Size | 10 mg |
Concentration | 0.1-10 µM. |
Applications | n/a |
Other Names | n/a |
Gene, Accession, CAS # | CAS: 169545-27-1 |
Catalog # | I-190 |
Price | please inquire |
Order / More Info | IRL 2500 from ALOMONE LABS |
Product Specific References | n/a |
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