A23187 from ALOMONE LABS

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Product NameA23187
DescriptionPurity: >98%. Effective Concentration: 1-10 μM. A23187, Calcimycin, Ca2+ Ionophore A23187, A23187 is a mobile-carrier Ca2+ ionophore (allows Ca2+ ions to cross cell membranes) originally isolated as an antibiotic from Streptomyces chartreusensis. It is used to increase intracellular Ca2+ levels, and for in vitro studies related to intracellular Ca2+ mediated events. A23187 can cause cell activation, differentiation, or proliferation and thus mimics cellular processes observed in response to cytokines and growth factors.Furthermore, A23187 induces in a concentration and time-dependent manner, Ca2+ triggered cell apoptosis. This property was exploited to clarify apoptotic events in different cell lines such as mouse lymphoma cell line (S49), histiocytic lymphoma U937, human myeloid leukemia cells (HL-60), cultured striatal neurons, renal tubular cells, and C6 glioma cells. Cell Ca2+ Signaling; Intracellular Ca2+ Mobilizers, Cell Signaling Activators and Inhibitors; Apoptosis Inducers. Cell Ca2+ Signaling; Intracellular Ca2+ Mobilizers. Cell Ca2+ Signaling; Ca2+ Ionophores.
Size1 mg
Concentrationn/a
Applicationsn/a
Other Namesn/a
Gene, Accession, CAS #n/a
Catalog #A-600
Price$27
Order / More InfoA23187 from ALOMONE LABS
Product Specific Referencesn/a
ALOMONE LABS
ALOMONE LABS
ALOMONE LABS
Jerusalem BioPark (JBP), Hadassah Ein Kerem
PO Box 4287
Jerusalem, 9104201 ISRAEL
P: +972-2-587-2202
F: +972-2-587-1101

info@alomone.com

http://www.alomone.com

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Toll free phone: 1800-618-1644 / 1800-791-3904

Toll free fax: 1888-454-7276 / 1800-791-3912


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