A-803467 from ALOMONE LABS

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Product NameA-803467
DescriptionPurity >99% (HPLC). A-803467 is a potent and selective blocker of the TTX-resistant Nav1.8 channel. A-803467 is a state dependent inhibitor with IC50 of 8 nM at depolarized membrane potential (-40 mV) and 80 nM at -100 mV. As an efficient inhibitor of TTX-resistant currents in DRG neurons, A-803467 was also effective as an analgesic in several rodent models of different pathological pain states. A-803467 was used as a pharmacological tool to demonstrate the expression of Nav1.8 in the heart conduction system and its contribution to QRS interval in the mouse heart. Synthetic. MW: 357.8
Size100 mg
Concentrationn/a
Applicationsn/a
Other Names5-(4-Chlorophenyl)-N-(3,5-dimethoxyphenyl)-2-furancarboxamide.
Gene, Accession, CAS #CAS: 944261-79-4
Catalog #A-105
Priceplease inquire
Order / More InfoA-803467 from ALOMONE LABS
Product Specific Referencesn/a
ALOMONE LABS
ALOMONE LABS
ALOMONE LABS
Jerusalem BioPark (JBP), Hadassah Ein Kerem
PO Box 4287
Jerusalem, 9104201 ISRAEL
P: +972-2-587-2202
F: +972-2-587-1101

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