|Product Name||Hydroxychloroquine Sulfate|
Hydroxychloroquine sulfate is used as an anti-malarial drug in regions where the parasite has grown resistance to chloroquine phosphate. It is a less toxic derivative of chloroquine phosphate that it known to inhibit proinflammatory cytokine levels and is being used as a treatment to decrease inflammation in autoimmune diseases such as rheumatoid arthritis and systemic lupus erythematosus. The drug is also broadly used to study autophagic pathways in eukaryotic cells, where it blocks lysosomal acidification. This decreases autophagic flux by disrupting autophagasome-lysosome fusion. Additionally, hydroxychloroquine sulfate inhibits infection by SARS-CoV-2 and other coronaviruses in vitro.
|Other Names||hydroxychloroquine, HCQ, chloroquine|
|Gene, Accession, CAS #||n/a|
|Order / More Info||Hydroxychloroquine Sulfate from BIOLEGEND|
|Product Specific References||PubMed: 32986722|