666-15 from BIOVISION, INC.

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Product Name666-15
DescriptionPurity 98.65%. MW: 620.52. 666-15 is a potent and selective inhibitor of cyclic adenosine monophosphate response element binding protein (CREB)-mediated gene transcription with an IC50 of 81 nM. The IC50 values for inhibiting the growth of A549, MCF-7, MDA-MB-231, MDA-MB-468 cell lines are 0.47 µM, 0.31 µM, 0.073 µM, 0.046 µM respectively. It is a weak inhibitor of CREB-CBP (CREB-binding protein) interaction with an IC50 of 18.27 µM. Intraperitoneal injection of 666-15 at 10 mg/kg/day, 5 days per week for 5 weeks suppresses tumor growth in an in vivo MDA-MB-468 xenograft model.
Size1 mg
Concentrationn/a
Applicationsn/a
Other Names3-(3-aminopropoxy)-N-[2-[3-[(4-chloro-2-hydroxyphenyl)carbamoyl]naphthalen-2-yl]oxyethyl]naphthalene-2-carboxamide, hydrochloride; 3-(3-Aminopropoxy)-N-(2-((3-((4-chloro-2-hydroxyphenyl)carbamoyl)naphthalen-2-yl)oxy)ethyl)-2-naphthamide hydrochloride; CREB 666-15; CREB Inhibitor; CBP-CREB Interaction Inhibitor II; Compound 3i
Gene, Accession, CAS #CAS: 1433286-70-4
Catalog #B2970-1
Price$95
Order / More Info666-15 from BIOVISION, INC.
Product Specific Referencesn/a
BIOVISION, INC.
BIOVISION, INC.
BIOVISION, INC.
155 S. Milpitas Boulevard
Milpitas CA 95035
P: 408-493-1800
P: 800-891-9699
F: 408-493-1801

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