666-15 from BIOVISION, INC.
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| Product Name | 666-15 |
| Description | Purity 98.65%. MW: 620.52. 666-15 is a potent and selective inhibitor of cyclic adenosine monophosphate response element binding protein (CREB)-mediated gene transcription with an IC50 of 81 nM. The IC50 values for inhibiting the growth of A549, MCF-7, MDA-MB-231, MDA-MB-468 cell lines are 0.47 µM, 0.31 µM, 0.073 µM, 0.046 µM respectively. It is a weak inhibitor of CREB-CBP (CREB-binding protein) interaction with an IC50 of 18.27 µM. Intraperitoneal injection of 666-15 at 10 mg/kg/day, 5 days per week for 5 weeks suppresses tumor growth in an in vivo MDA-MB-468 xenograft model. |
| Size | 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 3-(3-aminopropoxy)-N-[2-[3-[(4-chloro-2-hydroxyphenyl)carbamoyl]naphthalen-2-yl]oxyethyl]naphthalene-2-carboxamide, hydrochloride; 3-(3-Aminopropoxy)-N-(2-((3-((4-chloro-2-hydroxyphenyl)carbamoyl)naphthalen-2-yl)oxy)ethyl)-2-naphthamide hydrochloride; CREB 666-15; CREB Inhibitor; CBP-CREB Interaction Inhibitor II; Compound 3i |
| Gene, Accession, CAS # | CAS: 1433286-70-4 |
| Catalog # | B2970-1 |
| Price | $95 |
| Order / More Info | 666-15 from BIOVISION, INC. |
| Product Specific References | n/a |
BIOVISION, INC.
BIOVISION, INC.
155 S. Milpitas Boulevard
Milpitas CA 95035
P: 408-493-1800
P: 800-891-9699
F: 408-493-1801
support@biovision.com
http://www.biovision.com
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