AHCY Inhibitor Screening Kit (Fluorometric) from BIOVISION, INC.

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Product NameAHCY Inhibitor Screening Kit (Fluorometric)
DescriptionAdenosyl homocysteinase (AHCY) (EC 3.3.1.1) or S-adenosyl homocysteine hydrolase (SAHH); is an enzyme that catalyzes the reversible hydrolysis of S-Adenosyl Homocysteine (SAH) to adenosine and homocysteine. Inhibition of AHCY results in the accumulation of SAH, a product inhibitor of S-adenosyl methionine (SAM)-dependent methyltransferases. AHCY is an important target as an antiviral and anticancer drug. Several characterized SAH inhibitors inhibit some DNA viruses (e.g. Pox viruses) and some negative stranded RNA viruses (e.g.: Marburg virus, Ebola virus & rabies). In BioVision's AHCY Inhibitor Screening kit the homocysteine generated from the breakdown of SAH is measured using a Thiol Detecting Reagent resulting in enhanced fluorescence which is measured at Ex/Em = 392/482 nm. The AHCY reaction is reversible and hence Adenosine Deaminase is included in the reaction to ensure that the reaction proceeds towards hydrolysis of SAH. In the presence of AHCY inhibitor, there is a decrease in fluorescence of the Thiol Detecting Reagent.
Size100 assays
Concentrationn/a
ApplicationsScreening/characterizing/studying AHCY inhibitors
Other Namesn/a
Gene, Accession, CAS #n/a
Catalog #K326-100
Price$875
Order / More InfoAHCY Inhibitor Screening Kit (Fluorometric) from BIOVISION, INC.
Product Specific Referencesn/a
BIOVISION, INC.
BIOVISION, INC.
BIOVISION, INC.
155 S. Milpitas Boulevard
Milpitas CA 95035
P: 408-493-1800
P: 800-891-9699
F: 408-493-1801

support@biovision.com

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