Recombinant SARS-CoV-2 Papain-like Protease from BIOVISION, INC.

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Product NameRecombinant SARS-CoV-2 Papain-like Protease
Descriptionaa Glu1564-Lys1878. Purity >95%. MW: 38 kDa (6xHis tag at the N-terminus). SARS-CoV is an enveloped, single and positive-stranded RNA virus. Replication of the genomic RNA of SARS-CoV is mediated by replicase polyproteins that are processed by two viral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro). The chymotrypsin-like 3CLpro processes the replicase polyprotein at 11 sites, including cleaving itself from the polyprotein to generate a ?25-kDa protease product. Papain-like proteases have been shown to process the amino-terminal end of the replicase polyprotein to generate two or three replicase products. Proteolytic processing of the coronavirus replicase polyprotein is essential for generating a functional replication complex. Therefore, the coronavirus replicase-encoded proteases, 3CLpro and PLpro, are potential targets for antiviral drug development.
Size10 µg
Concentrationn/a
ApplicationsRUO
Other NamesPLPro, PL-PRO, pp1a, Papain-like Protease, Replicase polyprotein 1a, ORF1a polyprotein, Plpro
Gene, Accession, CAS #Accession: YP_009725299.1
Catalog #P1551-10
Price$105
Order / More InfoRecombinant SARS-CoV-2 Papain-like Protease from BIOVISION, INC.
Product Specific Referencesn/a
BIOVISION, INC.
BIOVISION, INC.
BIOVISION, INC.
155 S. Milpitas Boulevard
Milpitas CA 95035
P: 408-493-1800
P: 800-891-9699
F: 408-493-1801

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