Recombinant SARS-CoV-2 NSP8 from BIOVISION, INC.

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Product NameRecombinant SARS-CoV-2 NSP8
DescriptionThe target is expressed with the sequence Ala1-Gln198 of SARS-CoV-2 NSP8 with a His tag at the N-terminus. Purity ≥ 90% by SDS-PAGE. The replication of Coronavirus is operated by multiple non-structural proteins (nsps). The viral genomic RNA is translated from two open reading frames (ORFs), ORF1a and ORF1b. The encoded replicase polyproteins, pp1a and pp1ab, are further processed to produce nsps. The viral protease, 3CLpro cleaves to generate the NSP8 protein. NSP8 is a component of the coronavirus replicase polyprotein that forms a replication complex. It forms a dimer with NSP7 and subsequently assembles into a large hexadecameric structure, which participates in viral replication by acting as a primase. NSP8 was shown to have RNA-dependent RNA polymerase (RdRp) activity that is necessary for producing primers utilized by NSP12 which is normally considered to be the RdRp for SARS-CoV-2. MW: 24 kDa
Size50 µg
Concentrationn/a
ApplicationsRUO
Other NamesSARS-CoV-2 NSP8; COVID-19 NSP8; 2019-nCoV NSP8; Non-Structural Protein 8; nsp8
Gene, Accession, CAS #Accession: YP 009725304.1
Catalog #P1648-50
Price$325
Order / More InfoRecombinant SARS-CoV-2 NSP8 from BIOVISION, INC.
Product Specific Referencesn/a
BIOVISION, INC.
BIOVISION, INC.
BIOVISION, INC.
155 S. Milpitas Boulevard
Milpitas CA 95035
P: 408-493-1800
P: 800-891-9699
F: 408-493-1801

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