A01 from BOC SCIENCES

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Product NameA01
DescriptionA01 is a high affinity Smurf1 E3 ubiquitin ligase inhibitor (Kd = 3.7 nM), which attenuates Smurf1-mediated Smad 1/5 degradation and enhances BMP signaling. Study showed that it potentiated BMP-2-induced osteoblastic activity in C2C12 myoblasts and MC3T3-. Purity ≥98% by HPLC. MW: 512.93. Molecular Formula: C22H20ClF3N4O3S
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Other Names[4-[[4-Chloro-3-(trifluoromethyl)phenyl]sulfonyl]-1-piperazinyl][4-(5-methyl-1H-pyrazol-1-yl)phenyl]methanone; SMURF1 inhibitor A01
Gene, Accession, CAS #CAS: 1007647-73-5
Catalog #1007647-73-5
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Order / More InfoA01 from BOC SCIENCES
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