A-317491 from CAYMAN CHEMICAL COMPANY
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| Product Name | A-317491 |
| Description | A P2X3 and P2X2/3 receptor antagonist (Kis = 22-92 nM in a calcium influx assay); selective over other purinergic and neurotransmitter receptors, ion channels, and enzymes (IC50s = >10 µM); reduces thermal hyperalgesia induced by complete Freund's adjuvant in rats (ED50 = 30 µmol/kg, s.c.) and nociceptive responses to chemically-induced pain; chronic administration reduces early, but not late, phase pain in a mouse model of bone cancer; does not readily cross the blood-brain barrier and reduces pain responses when applied topically, |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | A 317491 P2X3 P2X2/3 purinoceptor cancer |
| Gene, Accession, CAS # | CAS: 475205-49-3 |
| Catalog # | 19256-10 |
| Price | $207.00 |
| Order / More Info | A-317491 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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