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Product Name | Bafilomycin A1 |
Description | A fungal metabolite with diverse biological activities; an inhibitor of V-ATPases (Ki = 0.5 nM in N. crassa vacuolar membranes); >1,000-fold selective for V-ATPases over Na+/K+-, Ca2+-, and H+-ATPases); inhibits autophagosome maturation and protein degradation in H-4-II-E cells at 100 nM; inhibits chloroquine-induced apoptosis in primary CGNs; reduces viral yield in the culture supernatant of SARS-CoV-2-infected Vero E6 and Huh7 cells, as well as HEK293T cells expressing human ACE2, at 100 nM; reduces lung RNA copy numbers and viral pneumonia in ACE2 transgenic mice infected with SARS-CoV-2 at 0.1 mg/kg |
Size | 5 mg |
Concentration | n/a |
Applications | n/a |
Other Names | NSC 381866 |
Gene, Accession, CAS # | CAS: 88899-55-2 |
Catalog # | 11038-5 |
Price | $775.00 |
Order / More Info | Bafilomycin A1 from CAYMAN CHEMICAL COMPANY |
Product Specific References | n/a |