A-769662 from CAYMAN CHEMICAL COMPANY

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Product NameA-769662
DescriptionA direct activator of AMPK (EC50 = 116 nM in a cell-free assay); allosterically activates AMPK and inhibits its dephosphorylation on Thr172; activates β1 subunit-containing AMPK heterotrimers; has been used to stimulate CYP450-mediated fatty acid oxidation, inhibit adipocyte differentiation, explore glucose uptake in skeletal muscle, and promote endothelial cell survival during metabolic stress
Size5 mg
Concentrationn/a
Applicationsn/a
Other Namesobesity syndromes kinases diabetes atherosclerosis AMP-activated proteins kinases AMPK lipids metabolisms glucose metabolic stress activators activates active glucose uptakes diseases A769662 A-769662 A 769662 A769,662 A 769,662 A-792,662 thienopyridone inhibits inhibiting inhibitions inhibitors CYP450 fatty acids oxidations adipocytes differentiations uptake up-take alpha .alpha. a beta .beta. b gamma .gamma. g heterotrimers sensors regulates regulating cells cellular energy homeostasis small molecules thienopyridones cell-free assays intact allosterically Thr172 stimulates CYP450-mediated cytochromes P450 dephosphorylations skeletal muscles endothelium endothelial
Gene, Accession, CAS #CAS: 844499-71-4
Catalog #11900-5
Price$69.00
Order / More InfoA-769662 from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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