Masitinib from CAYMAN CHEMICAL COMPANY
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| Product Name | Masitinib |
| Description | An inhibitor of c-Kit (IC50 = 200 nM); an inhibitor of PDGFRα, PDGFRβ, and Lyn B (IC50s = 540, 800, and 510 nM, respectively); inhibits stem cell factor-induced proliferation of Ba/F3 cells expressing wild-type KIT (IC50 = 150 nM), as well as those expressing the KIT mutants KITV559D and KITΔ27 (IC50s = 3 and 5 nM, respectively); an inhibitor of SARS-CoV-2 Mpro (Ki = 2.6 µM); inhibits replication of SARS-CoV-2 in infected A549 cells (EC50 = 3.2 µM); decreases lung and nose viral titers, as well as reduces lung inflammation and increases survival, in ACE2-humanized mice infected with SARS-CoV-2 at 25 mg/kg |
| Size | 25 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | AB-1010|Masican|Masiviera |
| Gene, Accession, CAS # | CAS: 790299-79-5 |
| Catalog # | 13105-25 |
| Price | $161.00 |
| Order / More Info | Masitinib from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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