Masitinib from CAYMAN CHEMICAL COMPANY

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Product NameMasitinib
DescriptionAn inhibitor of c-Kit (IC50 = 200 nM); an inhibitor of PDGFRα, PDGFRβ, and Lyn B (IC50s = 540, 800, and 510 nM, respectively); inhibits stem cell factor-induced proliferation of Ba/F3 cells expressing wild-type KIT (IC50 = 150 nM), as well as those expressing the KIT mutants KITV559D and KITΔ27 (IC50s = 3 and 5 nM, respectively); an inhibitor of SARS-CoV-2 Mpro (Ki = 2.6 µM); inhibits replication of SARS-CoV-2 in infected A549 cells (EC50 = 3.2 µM); decreases lung and nose viral titers, as well as reduces lung inflammation and increases survival, in ACE2-humanized mice infected with SARS-CoV-2 at 25 mg/kg
Size10 mg
Concentrationn/a
Applicationsn/a
Other NamesAB-1010|Masican|Masiviera
Gene, Accession, CAS #CAS: 790299-79-5
Catalog #13105-10
Price$60
Order / More InfoMasitinib from CAYMAN CHEMICAL COMPANY
Product Specific Referencesn/a
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640

Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com

http://www.caymanchem.com

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