Hexokinase Inhibitor Screening Kit from CREATIVE BIOMART

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Product NameHexokinase Inhibitor Screening Kit
DescriptionIn the Hexokinase Inhibitor Screening kit, glucose is converted to glucose-6-phosphate by hexokinase; the glucose-6-phosphate is oxidized by glucose-6-phosphate dehydrogenase to form NADH, which reduces a colorless probe to a colored product with strong absorbance at 450 nm. In the presence of a Hexokinase inhibitor, the reaction is impeded/abolished resulting in decrease or total loss of absorbance. This assay kit can be used to screen/study/characterize the potential inhibitors of Hexokinase. The assay is simple, high-throughput adaptable and can be performed within 30 min.
Size100 assays
Concentrationn/a
ApplicationsScreening/characterizing/studying potential inhibitors of Hexokinase
Other Namesn/a
Gene, Accession, CAS #Hexokinases (HK) play an important role in glucose metabolism. Hexokinases phosphorylate glucose and generate glucose-6-phosphate for glycolysis. Hexokinases have four isoforms (HK-I, II, III and IV). HK-I, HK-II and HK-III have low Km, while HK-IV has 100 fold high Km. Hexokinase deficiency leads to severe human diseases such as X-linked muscular dystrophy and a rare autosomal recessive hemolytic anemia. On the other hand, increased hexokinase activity is detected in various tumors and is associated with metastasis.
Catalog #Kit-2144
Priceplease inquire
Order / More InfoHexokinase Inhibitor Screening Kit from CREATIVE BIOMART
Product Specific Referencesn/a
CREATIVE BIOMART
CREATIVE BIOMART
CREATIVE BIOMART
45-1 Ramsey Road
Shirley NY 11967
P: 1-631-619-7922
F: 1-631-938-8127

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