SARS-CoV-2 Surrogate Virus Neutralization Test ELISA from EAGLE BIOSCIENCES INC.
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| Product Name | SARS-CoV-2 Surrogate Virus Neutralization Test ELISA |
| Description | Sample types: serum, plasma. Time: 3 hours. The GENLISA ELISA kits are used for assessing the specific biomarker in samples analytes which may be serum, plasma and cell culture supernatant as validated with the kit. The kit employs a blocking ELISA technique which mimics the virus neutralization process. SARS-CoV-2-neutralizing antibodies primarily target the trimeric spike (S) glycoproteins on the viral surface that mediate entry into host cells. The S protein has two functional subunits that mediate cell attachment (the S1 subunit, existing of four core domains S1A through S1D) and fusion of the viral and cellular membrane (the S2 subunit). Potent neutralizing antibodies often target the receptor interaction site in S1, disabling receptor interactions. The spike proteins of SARS-CoV-2 commonly bind to the human angiotensin coverting enzyme 2 (ACE2) protein as a host receptor through their S1B domain. Receptor interaction is known to trigger irreversible conformational changes in coronavirus spike proteins enabling membrane fusion. SARS-CoV-2 initiates an immune response, which leads to the production of antibodies. These neutralizing antibodies provide protection against future infection from SARS-CoV-2, as they remain in the circulatory system for months to years post infection. |
| Size | 1 x 96 well |
| Concentration | n/a |
| Applications | n/a |
| Other Names | assay, kit, test |
| Gene, Accession, CAS # | n/a |
| Catalog # | KBVH400 |
| Price | $695 |
| Order / More Info | SARS-CoV-2 Surrogate Virus Neutralization Test ELISA from EAGLE BIOSCIENCES INC. |
| Product Specific References | n/a |
EAGLE BIOSCIENCES INC.
EAGLE BIOSCIENCES INC.
20A NW Blvd., Suite 112
Nashua NH 03063
P: 617-419-2019
P: 866-411-8023
F: 617-419-1110
info@EagleBio.com
http://www.EagleBio.com
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