Active Human Recombinant Tau (K18) Delta K280 mutant Protein Monomer from EAGLE BIOSCIENCES INC.

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Product NameActive Human Recombinant Tau (K18) Delta K280 mutant Protein Monomer
DescriptionAlzheimer's Disease (AD) is the most common neurodegenerative disease, affecting 10% of seniors over the age of 65 (1). It was named after Alois Alzheimer, a German scientist who discovered tangled bundles of fibrils where neurons had once been in the brain of a deceased patient in 1907 (2). Tau (tubulin-associated unit) is normally located in the axons of neurons where it stabilizes microtubules. Tauopathies such as AD are characterized by neurofibrillary tangles containing hyperphosphorylated tau fibrils (3). The delta K280 mutation is associated with frontotemporal dementia and promotes fibrillization into paired helical filaments (PHFs) in the absence of heparin and other inducers (4). K18 is a truncated form of human tau containing only the 4 microtubule binding repeats (5).
Size100 µg
Concentrationn/a
ApplicationsRUO
Other Namesn/a
Gene, Accession, CAS #n/a
Catalog #SPR-476B
Price$525
Order / More InfoActive Human Recombinant Tau (K18) Delta K280 mutant Protein Monomer from EAGLE BIOSCIENCES INC.
Product Specific Referencesn/a
EAGLE BIOSCIENCES INC.
EAGLE BIOSCIENCES INC.
EAGLE BIOSCIENCES INC.
20A NW Blvd., Suite 112
Nashua NH 03063
P: 617-419-2019
P: 866-411-8023
F: 617-419-1110

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