17-AAG (CAS 75747-14-7) from LIFESPAN BIOSCIENCES INC.

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Product Name17-AAG (CAS 75747-14-7)
DescriptionA semi-synthetic derivative of Geldanamycin that displays greater stability and lower in vivo toxicity compared to Geldanamycin. Binds to Heat shock protein 90 (Hsp90) (EC50 = 7.2 µM) in a manner similar to geldanamycin. Exhibits 100-fold higher affinity for tumor-derived Hsp90 over normal cells. Also inhibits Akt activation and HER2 expression in tumor cells. Purity >98% by HPLC
Size1 mg, 5 mg
Concentrationn/a
Applicationsn/a
Other NamesTanespimycin, 17-(Allylamino)geldanamycin, 17-(Allylamino)-17-demethoxygeldanamycin, NSC330507
Gene, Accession, CAS #CAS: 75747-14-7
Catalog #LS-H2472
Priceplease inquire
Order / More Info17-AAG (CAS 75747-14-7) from LIFESPAN BIOSCIENCES INC.
Product Specific Referencesn/a
LIFESPAN BIOSCIENCES INC.
LIFESPAN BIOSCIENCES INC.
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