AAL-993 (CAS 269390-77-4) from LIFESPAN BIOSCIENCES INC.

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Product NameAAL-993 (CAS 269390-77-4)
DescriptionAAL-993 inhibits VEGFR-1 (IC50 = 130 nM), VEGFR-2 (IC50 = 23 nM), and VEGFR-3 (IC50 = 18 nM). PDGFR-b, cKit, and CSF-1R are also inhibited at higher concentrations (IC50's 640 nM, 236 nM and 380 nM respectively). Screening studies have shown no inhibitory activity against a range of other kinases. X-Ray crystallography has shown that AAL-993 binds to the catalytic domain of VEGFR-2 when the protein is in an inactive conformation. Cell permeable, active in vivo and in whole animal studies. Purity >98% by NMR, TLC
Size25 mg, 5 mg
Concentrationn/a
Applicationsn/a
Other Names2-[(4-Pyridyl)methyl]amino-N-[3-(trifluoromethyl)phenyl]benzamide
Gene, Accession, CAS #CAS: 269390-77-4
Catalog #LS-H14579
Priceplease inquire
Order / More InfoAAL-993 (CAS 269390-77-4) from LIFESPAN BIOSCIENCES INC.
Product Specific Referencesn/a
LIFESPAN BIOSCIENCES INC.
LIFESPAN BIOSCIENCES INC.
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