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Product Name | Human IFN-gamma/IL-2 SARS-CoV-2 FluoroSpotPLUS kit, pre-coated plates |
Description | The human IFN-γ/IL-2 SARS-CoV-2 FluoroSpot kit enables enumeration of T cells secreting either one or both analytes in response to SARS-CoV-2 peptides. The combination of IFN-γ and IL-2 enables the quantitation of polyfunctional specific T cells. The kit includes one low fluorescent plate pre-coated with monoclonal capture antibodies, SARS-CoV-2 S2 N defined peptide pool, SARS-CoV-2 S N M O defined peptide pool, and SARS-CoV-2 S1 scanning pool, monoclonal detection antibodies, secondary reagents conjugated to fluorophores, a fluorescence enhancer and an anti-CD28 monoclonal antibody for co-stimulation. A polyclonal activator for human T cells (mAb CD3-2) is supplied as a positive control for cytokine secretion. Pre-coated plates reduce assay time and minimize variability. |
Size | 1 plate |
Concentration | n/a |
Applications | FluoroSpot |
Other Names | FluoroSpot kit, assay, EIA, ELISA, enzyme immunoassay |
Gene, Accession, CAS # | Gene ID: 3458, 3558 |
Catalog # | FSP-0102-P1-1 |
Price | please inquire |
Order / More Info | Human IFN-gamma/IL-2 SARS-CoV-2 FluoroSpotPLUS kit, pre-coated plates from MABTECH AB |
Product Specific References | Carrasco Pro, S., et al. (2018). Microbiota epitope similarity either dampens or enhances the immunogenicity of disease-associated antigenic epitopes. PLoS ONE. (http://www.ncbi.nlm.nih.gov/pubmed/29734356)Oehrmalm, L., et al. (2013). Decreased functional T lymphocyte-mediated cytokine response in patients with chemotherapy-induced neutropenia. Journal of internal medicine. (http://www.ncbi.nlm.nih.gov/pubmed/23789642)Lund, G., et al. (2017). Strong and frequent T-cell responses to the minor allergen Phl p 12 in Spanish patients IgE-sensitized to Profilins. Allergy. (http://www.ncbi.nlm.nih.gov/pubmed/29121407)Liebowitz, D., et al. (2020). Efficacy, immunogenicity, and safety of an oral influenza vaccine: a placebo-controlled and active-controlled phase 2 human challenge study. Lancet Infect Dis. (http://www.ncbi.nlm.nih.gov/pubmed/31978354)Jackson, S. E., et al. (2017). Latent Cytomegalovirus (CMV) Infection Does Not Detrimentally Alter T Cell Responses in the Healthy Old, But Increased Latent CMV Carriage Is Related to Expanded CMV-Specific T Cells. Front Immunol. (http://www.ncbi.nlm.nih.gov/pubmed/28694811) |