666-15 from MED CHEM EXPRESS
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| Product Name | 666-15 |
| Description | 666-15 is a potent and selective CREB inhibitor with an IC50 of 81 nM. 666-15 suppresses tumor growth in a breast cancer xenograft model. Molecular Weight: 620. 52 Purity: 99. 74% |
| Size | 10 mM - 1 mL, 5 mg, 10 mg, 25 mg, 50 mg |
| Concentration | n/a |
| Applications | Bioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting... |
| Other Names | n/a |
| Gene, Accession, CAS # | CAS: 1433286-70-4 |
| Catalog # | HY-101120 |
| Price | $213, $156, $264, $552, $996 |
| Order / More Info | 666-15 from MED CHEM EXPRESS |
| Product Specific References | [3]. Zhang B, et al. C1q-TNF-related protein-3 attenuates pressure overload-induced cardiac hypertrophy by suppressing the p38/CREB pathway and p38-induced ER stress. Cell Death Dis. 2019 Jul 8;10(7):520.;[1]. Xie F, et al. Identification of a Potent Inhibitor of CREB-Mediated Gene Transcription with Efficacious in Vivo Anticancer Activity. J Med Chem. 2015 Jun 25;58(12):5075-87.;[2]. Qin Y, et al. Interfering MSN-NONO complex-activated CREB signaling serves as a therapeutic strategy for triple-negative breast cancer. Sci Adv. 2020 Feb 19;6(8):eaaw9960. |
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