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Product Name | Human CellExp Renin, Mouse Recombinant |
Description | Purity ≥95% by SDS-PAGE gel. Background: Renin, also known as REN and angiotensinogenase, is a circulating enzyme that participates in the body's renin-angiotensin system (RAS), and plays an essential role in the elevation of arterial blood pressure and increased sodium retention by the kidney. Renin activates the renin-angiotensin system by cleaving angiotensinogen, produced by the liver, to yield angiotensin I, which is further converted into angiotensin II by ACE, the angiotensin-converting enzyme primarily within the capillaries of the lungs. Renin is secreted from kidney cells, which are activated via signaling from the macula densa, which responds to the rate of fluid flow through the distal tubule, by decreases in renal perfusion. The protein is fused with 6xhis tag at the C-terminus and has a calculated MW of 43.2 kDa expressed. The predicted N-terminus is Leu24. Protein migrates as 45-55 kDa in reduced SDS-PAGE due to glycosylation. |
Size | 0.01 mg |
Concentration | n/a |
Applications | SDS-PAGE; HPLC |
Other Names | [CYMP; CYM; RENNIN; Chymosin], [Ren1; Ren1; Ren; Rnr; Rn-1; Ren-1; Ren-A; Ren1c; Ren1d; D19352; Ren; Ren-1] |
Gene, Accession, CAS # | [REN], Gene ID: 19701, NCBI: NP_112469.1, UniProt: P06281 |
Catalog # | MBS844162 |
Price | $205 |
Order / More Info | Human CellExp Renin, Mouse Recombinant from MYBIOSOURCE INC. |
Product Specific References | n/a |