Human CellExp SERPIN A8, Human Recombinant from MYBIOSOURCE INC.
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| Product Name | Human CellExp SERPIN A8, Human Recombinant |
| Description | Purity ≥98%. Background: Serpin A8 also known as angiotensinogen (AGT), is a member of the serpin family. It is an alpha-2-globulin that is expressed by the liver and secreted in plasma. As essential component of the renin-angiotensin system (RAS), Angiotensinogen is cleaved into three chains: Angiotensin-1 (Ang I), Angiotensin-2 (Ang II), and Angiotensin-3 (Ang III) in lowered blood pressure by the enzyme renin. Angiotensin-1 is a substrate of ACE (angiotensin converting enzyme) that removes a dipeptide to yield the physiologically active peptide angiotensin-2. Angiotensin-2 acts directly on vascular smooth muscle as a potent vasoconstrictor, affects cardiac contractility and heart rate through its action on the sympathetic nervous syst. The protein is fused with 6xHis tag at the N-terminus, has a calculated MW of 50.6 kDa. The predicted N-terminus is Asp 34. DTT-reduced Protein migrates as 55-60 kDa due to glycosylation. |
| Size | 0.01 mg |
| Concentration | n/a |
| Applications | SDS-PAGE; HPLC |
| Other Names | [Angiotensinogen; SerpinA8; AGT; ANHU], [AGT; AGT; ANHU; SERPINA8; SERPINA8; Ang I; Ang II; Ang III; Ang IV] |
| Gene, Accession, CAS # | [AGT], Gene ID: 183, NCBI: NP_000020.1, UniProt: P01019 |
| Catalog # | MBS844423 |
| Price | $290 |
| Order / More Info | Human CellExp SERPIN A8, Human Recombinant from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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