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Antigenic Specificity | SIRT5 |
Clone | O91G9 |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG2b, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB), KO/KD-Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-SIRT5. The seven mammalian Sirtuin isoforms are assigned to different Sirtuin classes on the basis of sequence homology. The mitochondrial SIRT5 belongs to class III. In the mitochondrial matrix, Sirt5 deacetylates and activates carbamoyl phosphate synthetase 1 (CPS1), which is increased when amino acid metabolism is upregulated during fasting. More importantly, SIRT5 regulates lysine succinylation and malonylation as evolutionarily conserved post-translation modifications. SIRT5 was proved to regulate |
Immunogen | Full length protein expressed in 293T cell transfected with human SIRT5 expression vector. |
Other Names | Sirtuin 5, SIR2L5, NAD-dependent protein deacylase sirtuin-5, mitochondrial, Regulatory protein SIR2 homolog 5, SIR2-like protein 5 |
Gene, Accession # | Gene ID: 23408 |
Catalog # | 698802 |
Price | $253 |
Order / More Info | SIRT5 Antibody from BIOLEGEND |
Product Specific References | n/a |