SPI1 (PU.1) Antibody from BIOLEGEND

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Antigenic SpecificitySPI1 (PU.1)
Clone7C2C34
Host SpeciesRat
Reactive Speciesmouse
IsotypeIgG2a, κ
FormatAlexa Fluor® 647 conjugate
Size25 µg
Concentrationn/a
ApplicationsIntracellular Staining for Flow Cytometry (ICFC)
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DescriptionAlexa Fluor® 647 anti-SPI1 (PU.1). SPI1 is a transcription factor that belongs to the E26-transformation-specific (ETS) family and is exclusively expressed in hematopoietic cells. SPI1 regulates cell fate decisions during the differentiation of hematopoietic stem cells, which is crucial for the development of lymphoid and myeloid cell lineages. SPI1-deficient mice lack macrophages, neutrophils, and B lymphocytes, and they die before or shortly after birth. Abnormally regulated expression of SPI1 can lead to developmental defects
ImmunogenFull length recombinant protein expressed in 293E cells.
Other NamesSpleen focus forming virus (SFFV) proviral integration oncogene, Sfpi1, Transcription factor PU.1, Dis1, PU.1, Dis-1, Sfpi1, Spi-1, Sfpi-1,Tcfpu1, Tfpu.1
Gene, Accession #Gene ID: 20375
Catalog #681303
Price$159
Order / More InfoSPI1 (PU.1) Antibody from BIOLEGEND
Product Specific ReferencesPubMed: 32259484, 33748781
BIOLEGEND
BIOLEGEND
BIOLEGEND
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San Diego CA 92121
P: (858) 455-9588
P: 1-877-Bio-Legend (246-5343)
F: (858) 455-9587

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