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Antigenic Specificity | SPI1 (PU.1) |
Clone | 7C6B05 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | Alexa Fluor® 647 conjugate |
Size | 100 tests |
Concentration | n/a |
Applications | Intracellular Staining for Flow Cytometry (ICFC), ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Alexa Fluor® 647 anti-SPI1 (PU.1). SPI1 is a transcription factor belonging to the E26-transformation-specific (Ets) family and is exclusively expressed in hematopoietic cells. SPI1 regulates cell fate decisions during differentiation of hematopoietic stem cells, which is crucial for the development of lymphoid and myeloid cell lineages. SPI1-deficient mice lack macrophages, neutrophils, and B lymphocytes, and they die before or shortly after birth. Abnormally regulated expression of SPI1 can lead to developmental defects as well |
Immunogen | Full length human SPI1 recombinant protein |
Other Names | Spleen focus forming virus (SFFV) proviral integration oncogene, Transcription factor PU.1 |
Gene, Accession # | Gene ID: 6688 |
Catalog # | 658004 |
Price | $382 |
Order / More Info | SPI1 (PU.1) Antibody from BIOLEGEND |
Product Specific References | PubMed: 31474513 |