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Antigenic Specificity | Spastin |
Clone | Sp3G11/1 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG2a, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-Spastin. Spastin is a microtubule-severing protein that cleaves longer microtubules (MTs) to shorter ones. The severing of MT regulates its numbers and mobility, and the distribution of the plus-end. This has also been related to membrane trafficking of microtubules. Mutations in the spastin gene SPG4 is the main cause for hereditary spastic paraplegia, a neurodegenerative disorder mainly occurring in corticospinal tracks. Due to the presence of 2 start codons in SPG4 gene, 2 isoforms of spastin exist: a |
Immunogen | Recombinant human spastin protein |
Other Names | Spastic paraplegia 4 protein, SPG4, ADPSP, FSP2 |
Gene, Accession # | Gene ID: 6683 |
Catalog # | 868202 |
Price | $276 |
Order / More Info | Spastin Antibody from BIOLEGEND |
Product Specific References | n/a |