Edit |   |
---|---|
Antigenic Specificity | TFEB |
Clone | W18197C |
Host Species | Rat |
Reactive Species | human |
Isotype | IgG2a, κ |
Format | Alexa Fluor® 647 conjugate |
Size | 100 tests |
Concentration | n/a |
Applications | Intracellular Staining for Flow Cytometry (ICFC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Alexa Fluor® 647 anti-TFEB. The autophagy-lysosomal pathway is required for the quality control degradation of proteins and other macromolecules. The transcription factor EB (TFEB) plays a critical role in inducing expression of genes involved in autophagy and lysosomal biogenesis. The subcellular localization and activity of TFEB are regulated by mechanistic target of rapamycin (mTOR)-mediated phosphorylation. Under nutrient-replete conditions, mTORC1 phosphorylates TFEB promoting its cytosolic retention by 14-3-3 protein |
Immunogen | Partial recombinant human TFEB protein |
Other Names | Transcription Factor EB |
Gene, Accession # | Gene ID: 7942 |
Catalog # | 936106 |
Price | $469 |
Order / More Info | TFEB Antibody from BIOLEGEND |
Product Specific References | n/a |