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Antigenic Specificity | Spectrin β1 |
Clone | N385/21 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG2a, κ |
Format | purified |
Size | 25 µg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-Spectrin β1. Spectrin β1 (SPTB1) is one of the several beta-spectrins that constitute the major components of the cytoskeletal network in erythrocyte plasma membrane. It binds another structural protein, band 4.1, to form a complex that anchors to the cytoplasmic face of the plasma membrane via Ankyrin, which in turn binds to protein band 3. Mutations in spectrin have been linked to hereditary defects in the erythrocyte, such as hereditary elliptocytosis. Recent studies show that caspase- and calpain-mediate |
Immunogen | n/a |
Other Names | SPTB, SPTB1 |
Gene, Accession # | Gene ID: 6710 |
Catalog # | 856901 |
Price | $83 |
Order / More Info | Spectrin β1 Antibody from BIOLEGEND |
Product Specific References | n/a |