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Antigenic Specificity | SHP-1 |
Clone | W17240D |
Host Species | Rat |
Reactive Species | human |
Isotype | IgG2b, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB), ICC, IP, Intracellular Staining for Flow Cytometry (ICFC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-SHP-1. SHP-1, also referred to as PTPN6 is an inhibitory protein phosphatase widely expressed in hematopoietic cell lineages that regulates cell cycle, proliferation, and inflammatory pathways. SHP-1 dephosphorylates activating signaling molecules in receptor tyrosine kinase pathways; in T cells it functions as a negative regulator of T cell activation and proliferation. SHP-1 is constitutively bound to the ITIM-containing adaptor molecules such as the inhibitory receptor LAIR-1; activation of SHP-1 re |
Immunogen | Partial recombinant protein corresponding to amino acid residues 1-213 of human SHP-1 |
Other Names | Protein Tyrosine Phosphatase, Non-Receptor Type 6, PTPN6, Hematopoietic Cell Protein-Tyrosine Phosphatase, Protein-Tyrosine Phosphatase SHP-1, Protein-Tyrosine Phosphatase 1C |
Gene, Accession # | Gene ID: 5777 |
Catalog # | 620302 |
Price | $253 |
Order / More Info | SHP-1 Antibody from BIOLEGEND |
Product Specific References | n/a |