LOXO-101 from CAYMAN CHEMICAL COMPANY
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| Product Name | LOXO-101 |
| Description | A pan-Trk inhibitor (IC50s = 2-20 nM for TrkA, TrkB, and TrkC); selective for TrkA, -B, and -C over a panel of 226 kinases at 1 µM; inhibits the growth of CUTO-3.29, KM12, and MO-91 patient-derived cancer cell lines (IC50s = <100, <10, and <10 nM, respectively); reduces tumor growth in a KM12 mouse xenograft model at 60 and 200 mg/kg , |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | ARRY-470|Larotrectinib |
| Gene, Accession, CAS # | CAS: 1223403-58-4 |
| Catalog # | 27056-10 |
| Price | $278.00 |
| Order / More Info | LOXO-101 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY