NSC 668036 from CAYMAN CHEMICAL COMPANY
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| Product Name | NSC 668036 |
| Description | An inhibitor of the Dvl PDZ domain (Kd = 240 µM for mouse Dvl1 PDZ domain); reduces expression of the Wnt target gene, Siamois, in Xenopus embryos and inhibits the ability of injected Wnt3A to induce formation of a secondary axis (180 ng); inhibits proliferation of NIH/3T3 fibroblasts, restrains their migration in a scratch assay, and blocks the accelerating effect of TGF-β on fibroblast migration (>10 µM); reduces the severity of bleomycin-induced pulmonary fibrosis and expression of α-SMA collagen I, TGF-β, and β-catenin in lung in mice (5 mg/kg per day for 14 days) |
| Size | 1 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | NSC668036 Wnt-3A TGFβ Dvl-1 αSMA |
| Gene, Accession, CAS # | CAS: 144678-63-7 |
| Catalog # | 23499-1 |
| Price | $37.00 |
| Order / More Info | NSC 668036 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
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