7-keto Cholesterol from CAYMAN CHEMICAL COMPANY
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| Product Name | 7-keto Cholesterol |
| Description | A bioactive oxysterol; a major oxysterol component of oxidized LDL; produced by oxidation of cholesterol via ethanol-mediated lipid peroxidation or photodamage as well as oxidation of 7-dehydro cholesterol by CYP7A1; inhibits CYP7A1 (IC50 = ~1 µM); induces activation and chemotaxis of retinal microglia as well as polarization to a pro-inflammatory state; increases ocular levels of VEGF, IL-1β, and GRO/KC, macrophage infiltration, and neovascularization in rat eye; levels are increased in lipid deposits in a variety of chronic diseases, |
| Size | 50 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | 7-oxo Cholesterol|SC-4722|Δ5-Cholesterol-3β-ol-7-one |
| Gene, Accession, CAS # | CAS: 566-28-9 |
| Catalog # | 16339-50 |
| Price | $412.00 |
| Order / More Info | 7-keto Cholesterol from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
Profile of CAYMAN CHEMICAL COMPANY