ICA 27243 from CAYMAN CHEMICAL COMPANY
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| Product Name | ICA 27243 |
| Description | An activator of Kv7.2/Kv7.3 subunit-containing channels; enhances rubidium efflux in an agonist-induced rubidium efflux assay using CHO cells expressing Kv7.2/Kv7.3 (EC50 = 0.38 µM); selective for Kv7.2/Kv7.3 channels over Kv7.4 channels (EC50 = 7.1 µM); 100-300-fold selective for Kv7.2/Kv7.3 over Kv7.3/Kv7.5 channels; selective for Kv7.2/Kv7.3 channels over a panel of neurotransmitter receptors and Nav1.2 at 10 µM, as well as GABAA receptors and high voltage-activated calcium channels at 30 µM; protects against maximal electroshock-induced seizures in a rat model of epilepsy (ED50 = 1.5 mg/kg); prevents amphetamine- and chlordiazepoxide-induced hyperactivity without affecting basal locomotor activity in a mouse model of manic-like hyperactivity at 10 mg/kg |
| Size | 10 mg |
| Concentration | n/a |
| Applications | n/a |
| Other Names | ICA 027243 |
| Gene, Accession, CAS # | CAS: 325457-89-4 |
| Catalog # | 40827-10 |
| Price | $184.00 |
| Order / More Info | ICA 27243 from CAYMAN CHEMICAL COMPANY |
| Product Specific References | n/a |
CAYMAN CHEMICAL COMPANY
CAYMAN CHEMICAL COMPANY
1180 East Ellsworth Road
Ann Arbor MI 48108
P: (734) 971-3335
P: (800) 364-9897 (USA & Canada only)
F: (734) 971-3640
Customer Service: custserv@caymanchem.com
Technical Support: techserv@caymanchem.com
Sales: sales@caymanchem.com
http://www.caymanchem.com
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